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Molecular Cancer Therapeutics

Molecular Cancer Therapeutics

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  • Current cover for Molecular Cancer Therapeutics
    Read the April 2018 Issue!
    Read the April 2018 Issue!
  • Editor's Pick: Relative Target Affinities of T-Cell–Dependent Bispecific Antibodies Determine Biodistribution in a Solid Tumor Mouse Model
    Editor's Pick: Relative Target Affinities of T-Cell–Dependent Bispecific Antibodies Determine Biodistribution in a Solid Tumor Mouse Model
    Danielle Mandikian, et al.
  • Pharmacological and Structural Characterizations of Naquotinib, a Novel Third-Generation EGFR Tyrosine Kinase Inhibitor, in EGFR-Mutated Non–Small Cell Lung Cancer
    Pharmacological and Structural Characterizations of Naquotinib, a Novel Third-Generation EGFR Tyrosine Kinase Inhibitor, in EGFR-Mutated Non–Small Cell Lung Cancer
    Toshiyuki Hirano, et al.
  • JAK2 Inhibitor SAR302503 Abrogates PD-L1 Expression and Targets Therapy-Resistant Non–small Cell Lung Cancers
    JAK2 Inhibitor SAR302503 Abrogates PD-L1 Expression and Targets Therapy-Resistant Non–small Cell Lung Cancers
    Sean P. Pitroda, et al.
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From the Current Issue

  • Review
    Engaging Anaphase Catastrophe Mechanisms to Eradicate Aneuploid Cancers
    Masanori Kawakami, Lisa Maria Mustachio, Xi Liu and Ethan Dmitrovsky
    Mol Cancer Ther April 1 2018 17 (4) 724-731; DOI:10.1158/1535-7163.MCT-17-1108

  • Small Molecule Therapeutics | AuthorChoice
    JAK2 Inhibitor SAR302503 Abrogates PD-L1 Expression and Targets Therapy-Resistant Non–small Cell Lung Cancers
    Sean P. Pitroda, Melinda E. Stack, Gene-Fu Liu, Sui-Sui Song, Lucy Chen, Hua Liang, Akash D. Parekh, Xiaona Huang, Paul Roach, Mitchell C. Posner, Ralph R. Weichselbaum and Nikolai N. Khodarev
    Mol Cancer Ther April 1 2018 17 (4) 732-739; DOI:10.1158/1535-7163.MCT-17-0667

  • Large Molecule Therapeutics
    Relative Target Affinities of T-Cell–Dependent Bispecific Antibodies Determine Biodistribution in a Solid Tumor Mouse Model
    Danielle Mandikian, Nene Takahashi, Amy A. Lo, Ji Li, Jeffrey Eastham-Anderson, Dionysos Slaga, Jason Ho, Maria Hristopoulos, Robyn Clark, Klara Totpal, Kedan Lin, Sean B. Joseph, Mark S. Dennis, Saileta Prabhu, Teemu T. Junttila and C. Andrew Boswell
    Mol Cancer Ther April 1 2018 17 (4) 776-785; DOI:10.1158/1535-7163.MCT-17-0657

  • Cancer Biology and Translational Studies
    Wnt/β-Catenin Pathway Activation Mediates Adaptive Resistance to BRAF Inhibition in Colorectal Cancer
    Guangming Chen, Chenxi Gao, Xuan Gao, Dennis Han Zhang, Shih-Fan Kuan, Timothy F. Burns and Jing Hu
    Mol Cancer Ther April 1 2018 17 (4) 806-813; DOI:10.1158/1535-7163.MCT-17-0561

  • Companion Diagnostic, Pharmacogenomic, and Cancer Biomarkers
    MCT4 Expression Is a Potential Therapeutic Target in Colorectal Cancer with Peritoneal Carcinomatosis
    Hee Kyung Kim, InKyoung Lee, Heejin Bang, Hee Cheol Kim, Woo Yong Lee, Seong Hyeon Yun, Jeeyun Lee, Su Jin Lee, Young Suk Park, Kyoung-Mee Kim and Won Ki Kang
    Mol Cancer Ther April 1 2018 17 (4) 838-848; DOI:10.1158/1535-7163.MCT-17-0535

  • Models and Technologies
    Characterizing the Potency and Impact of Carbon Ion Therapy in a Primary Mouse Model of Soft Tissue Sarcoma
    Jeremy M. Brownstein, Amy J. Wisdom, Katherine D. Castle, Yvonne M. Mowery, Peter Guida, Chang-Lung Lee, Francesco Tommasino, Chiara La Tessa, Emanuele Scifoni, Junheng Gao, Lixia Luo, Lorraine Da Silva Campos, Yan Ma, Nerissa Williams, Sin-Ho Jung, Marco Durante and David G. Kirsch
    Mol Cancer Ther April 1 2018 17 (4) 858-868; DOI:10.1158/1535-7163.MCT-17-0965

See the Table of Contents


Recent Reviews

  • Review
    Histone Methyltransferase EZH2: A Therapeutic Target for Ovarian Cancer
    Bayley A. Jones, Sooryanarayana Varambally and Rebecca C. Arend
    Mol Cancer Ther March 1 2018 17 (3) 591-602; DOI:10.1158/1535-7163.MCT-17-0437

  • Review
    Path toward Precision Oncology: Review of Targeted Therapy Studies and Tools to Aid in Defining “Actionability” of a Molecular Lesion and Patient Management Support
    Young Kwang Chae, Alan P. Pan, Andrew A. Davis, Sandip P. Patel, Benedito A. Carneiro, Razelle Kurzrock and Francis J. Giles
    Mol Cancer Ther December 1 2017 16 (12) 2645-2655; DOI:10.1158/1535-7163.MCT-17-0597

  • Review
    New B7 Family Checkpoints in Human Cancers
    Ling Ni and Chen Dong
    Mol Cancer Ther July 1 2017 16 (7) 1203-1211; DOI:10.1158/1535-7163.MCT-16-0761

OnlineFirst Articles

  • Induction of telomere damage to treat pediatric brain tumors
    Satarupa Sengupta, et al.
  • Hypersensitivity of BRCA1/2-deficient cells to APTO-253
    Cheng-Yu Tsai, et al.
  • A synthetic BRCA2 peptide inhibits RAD51
    Anika Trenner, et al.
  • MAPK reactivation facilitates resistance to FGFR inhibition
    Bruno Bockorny, et al.
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Copyright 2016 by the American Association for Cancer Research.

Molecular Cancer Therapeutics
eISSN: 1538-8514
ISSN: 1535-7163

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